Single and jobless, best friends Meg (Kate Upton) and Kate (Alexandra Daddario) are in a rough patch. When the pair decides to take a tropical vacation to escape the stress of their lives, a hurricane reroutes their flight to St. Louis for an extended layover. Stuck in a hotel with their fellow passengers, Meg and Kate suddenly find that their vacation has turned into an all-out competition for the same hot guy (Matt Barr) they met on the plane.