Tough & smart. Edgy & humorous. Rizzoli & Isles. Angie Harmon and Sasha Alexander star as combative, working-class Boston detective Jane Rizzoli and cool, cerebral medical examiner Dr. Maura Isles in an exciting police procedural with a compelling point of view, based on the bestselling novels by Tess Gerritsen. The two women have each other's backs as they investigate their city's grittiest and most puzzling homicides, from the Back Bay to back alleys. The high-caliber supporting cast includes Lorraine Bracco (The Sopranos) as Jane's overprotective mom. Some best friends shop together, some meet for Mojitos, some join book clubs. Rizzoli and Isles bust crime.